In the peak season of infectious diseases, immunity testing is hot!
1. Mycoplasma pneumoniae pneumonia
Mycoplasma pneumoniae pneumonia is an acute pulmonary infectious disease caused by Mycoplasma pneumoniae. Patients have fever and cough as the main clinical manifestations. The cough is severe and may be accompanied by headache, runny nose, sore throat, earache, etc. [1]. It is mainly transmitted through direct contact and droplets. People of all ages are generally susceptible, and children are the most susceptible. Since May this year, many places in southern my country have reported an increase in mycoplasma pneumonia infections, with a small number of families or classes gathering the disease. Compared with previous years, mycoplasma pneumonia in our country has become younger this year, with some children under 3 years old also suffering from the disease. .
2. Influenza
Influenza is an acute respiratory infectious disease caused by influenza viruses. The currently circulating seasonal influenza viruses include H3N2 subtype A, H1N1 subtype A (pdm09) and Victoria lineage B. The main clinical manifestations are systemic symptoms such as fever, muscle pain, headache, and fatigue, while local symptoms such as sore throat, runny nose, and nasal congestion are mild [2]. It is mainly transmitted through droplets, but can also be transmitted through direct or indirect contact with oral and nasal mucosa. People of all ages are generally susceptible.
3. Viral diarrhea
Viral diarrhea is an acute intestinal infectious disease that can be caused by a variety of viruses. The main pathogens include rotavirus (group A), norovirus (type I and type II), intestinal adenovirus, etc. [3], clinical The main symptoms are vomiting, fever and non-bloody diarrhea. It is mainly transmitted through the fecal-oral route, but can also be transmitted through the respiratory tract. Infants and young children aged 6 to 24 months are the main susceptible group, and the incidence rate is also high in children over 2 years old.
In the face of the above infectious diseases, some people are asymptomatic, some have mild symptoms, some have severe symptoms, and some people may even be infected twice. In addition to being related to the type of pathogen, load, and underlying diseases, It is also closely related to immune function. Immunity is the ability of our body to resist invasion by foreign bacteria, fungi, viruses and other harmful substances, or to eliminate damaged cells and tumor cells produced by the body. If the immunity is low, external pathogens cannot be effectively resisted and eliminated, resulting in bacterial or viral infections [4]. TBNK lymphocytes are key effector cells of the immune system. Their changes may indicate changes in the body's immune status and can be used to monitor whether there is an immune imbalance (hyperimmunity or hypoimmunity) in the body.
Since the COVID-19 epidemic, immunity has received unprecedented attention. In response to the health needs of the times, the Health Management Branch of the Chinese Medical Association has published three expert consensus articles since 2023 to popularize and standardize the detection of TBNK lymphocytes by flow cytometry. Application in health management
